Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila.
The systemic immune response of Drosophila is known to be induced both by septic injury and by oral infection with certain bacteria, and is characterized by the secretion of antimicrobial peptides (AMPs) into the haemolymph.To investigate other possible routes of bacterial infection, we deposited Erwinia carotovora (Ecc15) on various sites of the c